Immunogenetic Association of 127 Human Leukocyte Antigen (HLA) Alleles with 30 Cancers in Continental Western European Countries
نویسندگان
چکیده
Human leukocyte antigen (HLA) genes have been associated with susceptibility and protection against a number of cancers. Here we used an immunogenetic epidemiological approach to evaluate the overall influence 127 HLA Class I II alleles on 30 types cancer. We found preponderance protective (negatively correlated cancer prevalences), especially for I. Of cancers investigated, 13 were mostly effects whereas only 2 alleles. Taken together, these findings highlight broad complexity HLA-cancer associations.
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ژورنال
عنوان ژورنال: Journal of immunological sciences
سال: 2022
ISSN: ['2578-3009']
DOI: https://doi.org/10.29245/2578-3009/2022/2.1227